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neuroimmune system : ウィキペディア英語版
neuroimmune system

The neuroimmune system is a system of biochemical and electrophysiological interactions between the nervous system and immune system. It serves to protect neurons in the brain and body against disease by maintaining selectively permeable barriers, mediating neuroinflammation and wound healing, and mobilizing host defenses against pathogens.〔〔
==Structure==

The key cellular components of the neuroimmune system are glial cells, including astrocytes, microglia, and oligodendrocytes.〔〔 Unlike other hematopoietic cells of the peripheral immune system, mast cells naturally occur in the brain where they mediate interactions between gut microbes, the immune system, and the central nervous system as part of the microbiota-gut-brain axis.
G protein-coupled receptors that are present in both CNS and immune cell types and which are responsible for a neuroimmune signaling process include:
*Chemokine receptors: CXCR4
*Cannabinoid receptors: CB1, CB2, GPR55
*Trace amine-associated receptors: TAAR1
*μ-Opioid receptors - all subtypes

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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